The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review

A Giwercman, NE Skakkebæk - International journal of …, 1986 - Wiley Online Library
… are responsible for the effects on male fertility (O’… review our present knowledge on the
effects of SASP and other sulphonamides on male fertility and to discuss their potentials as male

Sulphasalazine: a review of 40 years' experience

G Watkinson - Drugs, 1986 - Springer
… flammatory bowel disease: effects of salicylazosulfapyridine (Azulfidine). Gastroenterology …
On the efficacy of ready made up commercially available salicylazosulphapyridine enemas in …

The effects of sulfasalazine on human male fertility potential and seminal prostaglandins

MJ Cosentino, WY Chey, H Takihara, ATK Cockett - The Journal of urology, 1984 - Elsevier
… Indeed, we recently reviewed the relationship of seminal prostaglandins to male fertility.Thus,
the … and Price Evans, DA: Metabolism of salicylazosulfapyridine in healthy subjects and in …

Oxidative stress as a mechanism underlying sulfasalazine-induced toxicity

V Linares, V Alonso, JL Domingo - Expert opinion on drug safety, 2011 - Taylor & Francis
… ’, ‘hepatotoxicity’ and ‘male fertility’. Original papers were reviewed and relevant citations …
In contrast to its effects on men, sulfasalazine is among the preferred disease-modifying …

Immunosuppressants and male reproduction

EZ Drobnis, AK Nangia, EZ Drobnis… - … on Male Fertility, 2017 - Springer
… are likely to impact negatively on male fertility endpoints, but … As we review in this chapter,
results in experimental species … negative effect of sulfasalazine on semen quality and fertility. …

Sulfasalazine: adverse effects and desensitization

SL Taffet, KM Das - Digestive diseases and sciences, 1983 - Springer
… This article reviews the recent literature on the side effects of sulfasalazine and discusses …
accumulation of folate was an effect of the intact salicylazosulfapyridine molecule, and this …

[HTML][HTML] Reversible germ cell toxicity of sulphasalazine and ampicillin combination in male rats

H Gupta, KK Maheshwari, N Kumar - Journal of Reproduction & …, 2013 - ncbi.nlm.nih.gov
effect of ampicillin (AMP, 40 mg/kg) and sulphasalazine or salicylazosulfapyridine (SASP, …
function of major elements of male fertility as reflected by the marked reduction in percentage …

Sulphasalazine in arthritis—an old drug rediscovered

AJ Taggart - Clinical Rheumatology, 1987 - Springer
Sulphasalazine (salicyl-azo-sulphapyridine) has been in clinical use for over 40 years.
Although the drug was originally introduced for the treatment of "rheumatic polyarthritis" and …

[HTML][HTML] Inflammatory bowel diseases and human reproduction: a comprehensive evidence-based review

S Palomba, G Sereni, A Falbo, M Beltrami… - World journal of …, 2014 - ncbi.nlm.nih.gov
Male fertility is restored two months after sulfasalazine … One study found an association
between sulfasalazine use in men … 5-ASA (except sulfasalazine) for men planning to conceive. …

Quercetin and rutin ameliorates sulphasalazine‐induced spermiotoxicity, alterations in reproductive hormones and steroidogenic enzyme imbalance in rats

SO Osawe, EO Farombi - Andrologia, 2018 - Wiley Online Library
… This adverse effect of SASP on male reproduction has been linked to the nontherapeutic SP
… Osawe of ICT Department, NABTEB, Benin City, are also appreciated for the English review